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Stop Checking Compliance Boxes: Start Measuring Proficiency to Drive Business Results
It’s standard in corporate learning models to use LMSs, but these learning systems weren’t designed for skill-building. And traditionally, industry-wide success with those systems has been defined by course completion metrics rather than proficiency. This doesn't truly demonstrate L&D’s business value to managers and executives. Corporate training and development is moving away from traditional methods and towards a microlearning strategy that empowers learning professionals with the tools to efficiently upskill and reskill a workforce and deliver business results. This white paper will go in depth on the benefits of modernizing your learning approach, with insights on how microlearning courses and its analytics help employees acquire important new skills and knowledge that align with business objectives.
Tue, 14 Sep 2021
Live Webinar: Unravel the Mystery of Office 365®
Do you find the many features of Office 365 confusing? You're not alone! Join award-winning productivity blogger and best-selling author Mike Song as he shares practical strategies that help you understand, organize, and manage your digital world. You will discover how Office 365 can help you save time and get more done. - Compare and contrast the desktop, browser, and mobile versions of 365 apps. - Learn better ways to share, collaborate, and manage your documents. - Optimize 365 settings, shortcuts, templates, and navigation. - Explore new apps like Teams, Planner, and Forms while learning handy. Windows 10 tips and tricks. This webinar is complimentary. Can’t make it? Don’t worry. Every registrant will receive a link to the recording.
Thu, 16 Sep 2021
Words of Wisdom: Expert Advice On Designing A Blended Learning Program
What is the best thing about a blended learning program You can harness all the benefits of technology-enabled learning without having to sacrifice the in-person elementThis post was first published on eLearning Industryhttpselearningindustrycom
Mon, 20 Sep 2021
Netflix launches free plan in Kenya to boost growth
Netflix said on Monday it is launching a free mobile plan in Kenya as the global streaming giant looks to tap the East African nation that is home to over 20 million internet usersThe free plan which will be rolled out to all users in Kenya in the coming weeks wont require them to provide any payment information during the sign-up the company said The new plan is available to any user aged 18 or above with an Android phone the company said It will also not include adsNetflix available in over 190 countries has experimented with a range of plans in recent years to lure customers in developing markets For instance it began testing a 3 mobile-only plan in India in 2018httpstechcrunchcom20181114netflix-is-testing-a-mobile-only-subscription-to-make-its-service-more-affordable before expandinghttpstechcrunchcom20191024netflix-malaysia-mobile-only-cheap-plan it to users in several other countriesThis is also not the first time Netflix is offering its service for free or at little to no price The company has previously supported free trials in many markets offered a tiny portionhttpstechcrunchcom20200831now-streaming-on-netflix-globally-free-original-shows-and-movies-to-non-subscribers of its original movies and shows to non-subscribers and has run at least one campaign in India when the service was available at no charge over the course of a weekendhttpstechcrunchcom20201020netflix-to-test-free-weekend-long-access-in-indiaBut its latest offering in Kenya is still remarkable The company told Reutershttpswwwreuterscomarticleus-netflix-kenya-idUSKBN2GG1LY that it is making about one quarter of its movies and television shows catalog available to users in the free plan in the East African nationIf youve never watched Netflix before and many people in Kenya havent this is a great way to experience our service Cathy Conk Director of Product Innovation at Netflix wrote in a blog posthttpsaboutnetflixcomennewsnetflix-launches-free-plan-in-kenyaAnd if you like what you see its easy to upgrade to one of our paid plans so you can enjoy our full catalog on your TV or laptop as wellThe company didnt disclose how long it plans to offer this free tier in Kenya and whether it is considering expanding this offering to other marketsOn its past earnings calls Netflix executives have insisted that they study each market and explore ways to make their service more compelling to all The ability to sign up without a payment information lends credibility to such claims Many individuals in developed countries dont have a credit or debit card rendering services requiring such payment instruments at the sign-up unattractive to themThe new push to win customers comes as the company which is also planning to add mobile games to its offeringhttpstechcrunchcom20210720netflix-says-its-gaming-push-will-begin-with-mobile added only 15 million net paying subscribers in the quarter that ended in June this year lower than what it had forecast Netflix which has amassed over 209 million subscribers as well as Amazon Prime Video and other streaming services are increasingly trying to win customers outside of the US to maintain faster growth ratesEarlier this year Amazon introduced a free and ad-supported video streaming servicehttpstechcrunchcom20210515amazon-minitv-free-streaming-service-india within its shopping app in India to tap more customers
Mon, 20 Sep 2021
VC Mark Suster: “The bet we’re making now is on founder skills,” not customers or products
We recently caught up with longtime VC Mark Suster of LA-based Upfront Ventureshttpsupfrontcom which last raised both an early-stage fund and a growth stage fund several years ago and according to regulatory filingshttpswwwsecgovArchivesedgardata1813608000181360820000002xslFormDX01primarydocxml is in the markethttpswwwsecgovArchivesedgardata1788021000178802119000001xslFormDX01primarydocxml right now though Suster couldnt discuss either owing to SEC regulationsWe did talk about a wide range of things from his firms big bet on the micromobility business Bird which could be publicly traded soonhttpssecreportDocument0001193125-21-265593 to his views on decentralized finance to his fitness regime we had to ask as Suster has shed 60 pounds since early last year If youre curious to hear that conversation you can listen herehttpspodcastsapplecomuspodcastupfront-ventures-mark-suster-on-investing-in-a-fastid1498270180i1000534279721 In the meantime what follows are outtakes of his reflections on broader industry trends including the feverish pace of deal-makingOn changing seed-stage check sizes and how much time VCs have to write them right nowIt used to be 10 years ago that I could write a 3 million or 4 million or 5 million check and that was called an A round and that company probably had raised a few hundred thousand dollars from angels and maybe some seed funds and I could get a lot of data on how companies were doing I could talk to customers I could look at customer retention I could look at a startups marginal cost structure I could talk to references of the founders I could take my time and be thoughtfulFast-forward a decade and 5 million is a seed round and now there are pre seed rounds and day zero companies and seed extensions and A rounds and A prime theres B Im not actually doing anything differently than I did 10 years ago in terms of deploying capital getting involved with founders very early helping you build your executive team set your strategy work on pricing figure out which market are you in figure out the sequence of how you launch products and how to raise downstream capital But the pressure on me is I now need to make faster decisions I need to be involved with your company earlier So Im taking a little more risk in terms of not being able to look at customers You may not even have customersOn why his firm is averse to todays A and B rounds and leaning more heavily into growth rounds It just brought aboard a former Twitter exechttpstechcrunchcom20210903catching-up-with-twitters-most-recent-head-of-corp-dev-and-new-vc-seksom-suriyapa to lead the charge here and has meanwhile plugged more than 50 million in to several of its portfolio companies including Bird Rally an investing platform for buying shares in collectibles and Apeel Sciences which makes edible coatings for fruitI would never rule out any round But what I will tell you is that the new A round that I maybe have an aversion to is call it 20 million to 30 million What does that imply It implies that youre paying a 50 million 60 million 70 million valuation It implies that to really drive fund-level returns you have to have 5 billion 10 billion or 15 billion outcomes or greaterThe world is producing more of those There are maybe 11 companies in the United States that are pure startups that are worth more than 10 billion I get it But if you want to be writing 20 million A rounds where youre taking that level of risk you have to have a 700 million to an 800 million to a 1 billion fund And I dont want to be in that business not because I think its bad but its a different business that implies different skillsWe want to be super early like the earliest capital well even take a risk on you want to leave your company and weve known you Lets say we knew you at Riot Games we knew you at Snapchat we knew you at Facebook we knew you when you were working at Stripe or PayPal We will back you at formation at day zero We want to then skip the expensive rounds and come in later Talking shop with Twitters recent head of corp dev and now VC Seksom Suriyapahttpstechcrunchcom20210903catching-up-with-twitters-most-recent-head-of-corp-dev-and-new-vc-seksom-suriyapaOn whether Upfront invests in priced rounds as well as convertible notes wherein an investor is entitled to invest at a discount to the next roundI think theres a lot of misnomers that rounds themselves arent priced Almost every round is priced People just think theyre not priced So maybe the question is Are we willing to do convertible notes are we willing to do SAFE notes are we willing to do all this stuff and the answer is yes Now most convertible notes most SAFE notes they dont fix a price but they have a cap And the cap is the price What I always try to tell founders is what you have is a maximum price with no minimum price If you were willing to just raise capital and set the price youd have a maximum and its better for you But for whatever reason a generation of founders has been convinced that its better not to set a price which really what theyre doing is setting a max not a minimum and Im not going to have that argument again People dont understand it The short version is we will do convertible notes we would not fund something that had no maximum priceRegarding how Upfront competes in a world where deals are happening within shorter time windows than ever beforeIf youre looking for a firm that will invest after one call youre calling the wrong firm We dont have as much time to know if customers love your product You may not even have customers But please dont mistake that We spend as much time as we can getting to know the founders We might know the founders for five years before they create a company We might be the people egging them on to quit Disney and go create a company So we really want to know the founder The bet that were making is now more on the founder skills and vision than on customer adoption of a product Thats really whats changed for usI always tell founders If someone is willing to fund you after a 30-minute meeting thats a really bad trade for you If a fund is doing 35 investments or 50 investments or even 20 investments and they get it wrong because they didnt do due diligence OK well they have 19 or 30 other investments If you get it wrong and you chose an investor whos not helpful not ethical not leaning in not supportive not adding value you live with that Theres no divorce clause
Mon, 20 Sep 2021
MIT study finds Tesla drivers become inattentive when Autopilot is activated
By the end of this week potentially thousands of Tesla owners will be testing out the automakers newest version of its Full Self-Driving beta softwarehttpstechcrunchcom20210920the-station-gogoro-scoots-into-a-spac-a-rivian-milestone-and-tesla-prepares-to-unleash-fsd-beta-software version 1001 on public roads even as regulators and federal officials investigate the safety of the systemhttpstechcrunchcom20210816u-s-safety-regulator-opens-investigation-into-tesla-autopilot-following-crashes-with-parked-emergency-vehicles after a few high-profile crashesA new study from the Massachusetts Institute of TechnologyhttpswwwsciencedirectcomsciencearticlepiiS0001457521003791via3Dihub lends credence to the idea that the FSD system which despite its name is not actually an autonomous system but rather an advanced driver assist system ADAS may not actually be that safe Researchers studying glance data from 290 human-initiated Autopilot disengagement epochs found drivers may become inattentive when using partially automated driving systems US safety regulator opens investigation into Tesla Autopilot following crashes with parked emergency vehicleshttpstechcrunchcom20210816u-s-safety-regulator-opens-investigation-into-tesla-autopilot-following-crashes-with-parked-emergency-vehiclesVisual behavior patterns change before and after Autopilot disengagement the study reads Before disengagement drivers looked less on road and focused more on non-driving related areas compared to after the transition to manual driving The higher proportion of off-road glances before disengagement to manual driving were not compensated by longer glances aheadTesla CEO Elon Musk has said that not everyone who has paid for the FSD software will be able to access the beta version which promises more automated driving functions First Tesla will use telemetry data to capture personal driving metrics over a seven-day period in order to ensure drivers are still remaining attentive enough The data may also be used to implement a new safety rating page that tracks the owners vehicle which is linked to their insuranceThe MIT study provides evidence that drivers may not be using Teslas Autopilot AP as recommended Because AP includes safety features like traffic-aware cruise control and autosteering drivers become less attentive and take their hands off the wheel more The researchers found this type of behavior may be the result of misunderstanding what the AP features can do and what its limitations are which is reinforced when it performs well Drivers whose tasks are automated for them may naturally become bored after attempting to sustain visual and physical alertness which researchers say only creates further inattentivenessThe report titled A model for naturalistic glance behavior around Tesla Autopilot disengagements has been following Tesla Model S and X owners during their daily routine for periods of a year or more throughout the greater Boston area The vehicles were equipped with the Real-time Intelligent Driving Environment Recording data acquisition system1 which continuously collects data from the CAN bus a GPS and three 720p video cameras These sensors provide information like vehicle kinematics driver interaction with the vehicle controllers mileage location and drivers posture face and the view in front of the vehicle MIT collected nearly 500000 miles worth of dataThe point of this study is not to shame Tesla but rather to advocate for driver attention management systems that can give drivers feedback in real time or adapt automation functionality to suit a drivers level of attention Currently Autopilot uses a hands-on-wheel sensing system to monitor driver engagement but it doesnt monitor driver attention via eye or head-trackingThe researchers behind the study have developed a model for glance behavior based on naturalistic data that can help understand the characteristics of shifts in driver attention under automation and support the development of solutions to ensure that drivers remain sufficiently engaged in the driving tasks This would not only assist driver monitoring systems in addressing atypical glances but it can also be used as a benchmark to study the safety effects of automation on a drivers behaviorCompanies like Seeing Machines and Smart Eye already work with automakers like General Motors Mercedes-Benz and reportedly Ford to bring camera-based driver monitoring systems to cars with ADAS but also to address problems caused by drunk or impaired drivinghttpstechcrunchcom20210805drunk-driving-provision-could-fuel-demand-for-driver-detection-technology The technology exists The question is will Tesla use it
Mon, 20 Sep 2021
‘Don’t get vaccinated’ truck touting ‘funeral home’ goes viral
In the age of misinformation aiming to increase vaccine confidence while simultaneously calling out anti-vax sentiment is quite a tricky taskAn ad campaign attempting to do just that has gone viral on Twitterhttpstwittercomyourgeniushandsstatus1439611078200147969 after a user posted a photo of a truck driving around Bank of America Stadium in Charlotte prior to Sundays game between the Panthers and the Saints The truck trumpeted the message Dont get vaccinated with Wilmore Funeral Home listed as its benefactor RexChapmanhttpstwittercomRexChapmanrefsrctwsrc5Etfw davenewworld2httpstwittercomdavenewworld2refsrctwsrc5Etfw This truck is making laps around Bank of America Stadium before the Panthers game in Charlotte pictwittercomrIW9OTltK5httpstcorIW9OTltK5 d yourgeniushands September 19 2021httpstwittercomyourgeniushandsstatus1439611078200147969refsrctwsrc5EtfwIn reality Wilmore Funeral Home doesnt appear to exist Its website is merely a mostly blank pagehttpswilmorefuneralhomecom featuring a Get vaccinated now box clicking on it takes users to Charlotte provider StarMed Healthcarehttpsstarmedcarevaccine and a page providing credible vaccine informationThe ad prompted lively debate across social media with some people appreciating the cleverness of the approach and others believing it was realIts a smart marketing campaign that gets people talking said Andrew Miller SVP of search and emerging media at CMI Media Group The shock value gets you the eyeballs and the attention As a marketer its exciting to see that because finding your audience is not always an easy thingThough its unclear exactly who launched the campaign or what prompted the unique approach a phone number underneath the ad on the truck directs to Crenshaw Visionshttpscrenshawvisionscom an ad agency based in Lancaster South CarolinaThe campaign seemingly plays on the notion that in the current era of misinformation people will interpret messaging in a manner that suits their own ideals and beliefs Miller questioned whether the campaign represented an attempt to reach anti-vaxxers and point that out to themIf youre targeting the audience thats anti-vaxxer and you get them interested and engaged and theyre getting to your website youre changing their point of view by giving them the chance to see that information they may not have otherwise Miller explainedThe misinformation part is something we deal with in healthcare a lot and it should be an increased focus for brands in general Finding ways to support brand content with authoritative vetted sources is important because then you have the ability to combat the misinformation partMiller added a caveat That while the campaign may be clever it plays on an idea that isnt actually funny at all which is that vaccine hesitancy has sent many people to real funeral homesThis is a risk that some companies and brands are willing to take to get the message across he said
Mon, 20 Sep 2021
Sandy Hook Promise shows real gun violence victims who lost their ‘Teenage Dream’
Teenage years are often romanticized as the most fun-filled of life with budding romances adventures with friends and a hopeful future on the horizonBut for an increasing number of high school students teenage years are marred with gun violence Sandy Hook Promise a nonprofit founded by parents who lost their children to gun violence released its latest PSA Teenage Dream to reflect those lost yearsIn the PSA created by BBDO New York and Smuggler director Henry-Alex Rubin a group of students recite the lyrics to Katy Perrys song Teenage Dream The song typically an upbeat anthem is noticeably somber with different high school students quietly singing the lyricsYou think Im pretty without any makeup on the lyrics read You think Im funny when I get the punchline wrong I know you get me so I let my walls come down Before you met meI was alright but things were kinda heavy You brought me to lifeThe spot ends with a warning that The teenage dream is not what it used to be and reveals that each student featured in the video is a victim of school gun violenceThe participants include Hannah Dysinger who was shot in the ribcage with the same bullet that killed her best friend Nick Walczak who was shot three times and paralyzed by a bullet in his spine Carlitos Rodriguez who barricaded himself behind a door as 17 of his schoolmates were killed in the Stoneman Douglas High School shooting in Parkland Florida Aalayah Eastmond a Parkland survivor who hid under the body of her dead friend Nolan Brandy who was shot in the kidney during class as his teacher and a classmate were killed in San Bernardino California Mia Page-Tretta who was shot in the stomach while her best friend was killed next to her and morePerrys song was the perfect fit for the PSA because of its hard-hitting lyrics Peter Alsante BBDO executive creative director told Campaign USIts easy to think back to some of the simpler times and how impermanent so much high school stuff is said Alsante Theyre just these fun years we look back on like Man if only life was that easy We knew that setting it against the very different experience these survivors of school shootings have had would create something really powerful and movingThe PSA aims to drive awareness of Sandy Hook Promise but also to spark discussion around how gun violence is preventableThe greatest measure of success will be that one day hopefully sooner rather than later a trend goes in the opposite direction and theres less of these types of shootings said AlsanteIn May Sandy Hook Promise deviated away from its usual gun violence campaigns to target mental health challenges in youth and teenshttpswwwcampaignlivecomarticlesandy-hook-promises-new-psas-highlight-mental-health-challenges-faced-youth1716031 caused by social distancing and a global health crisisThis article originally appeared on Campaign US
Mon, 20 Sep 2021
5 Keys to Success for Market Research
The market research industry is at a crossroads ready to solve critical challenges and move forward Some current issues include- The demand for survey respondents for online panels surpasses the supply- Consumers want to participate in market research differently than before- Customers have data privacy concernsHowever change takes time resources and a shift in mindset There are 5 key considerations for market researchers to stay competitive and succeed in todays marketplaceWhat are these keys to market research successRegister todayhttpswwwgreenbookorgmarketing-researchwebinar-5-Keys-to-Success-for-Market-Research to learn- Whats driving change in the market research industry- The 5 secrets to success for market researchers and how to stay competitive- How to unlock growth opportunities for your career and your businessSpeakerNancy Brigham VP Head of Research ScienceThe post 5 Keys to Success for Market Researchhttpswwwgreenbookorgmrmarketing-research5-keys-to-success-for-market-research first appeared on GreenBookhttpswwwgreenbookorgmr
Mon, 20 Sep 2021
Intouch Group promotes two to president
Intouch Group announcedhttpsmarketsbusinessinsidercomnewsstocksintouch-group-promotes-angela-tenuta-and-boris-kushkuley-to-president-roles-1030789386 two senior-level promotions naming Angela Tenuta president full-service agencies and Boris Kushkuley president commercial and consulting servicesIn her new role Tenuta formerly EVP of client services will provide operations oversight for the groups three full-service agencies Intouch Solutions Intouch Proto and Intouch SevenKushkuley who helped establish Intouchs East Coast operation since joining in 2014 will lead the New York office and continue to lead strategic services as well as expand the groups commercialization consulting services
Mon, 20 Sep 2021
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Salesforce economy set to generate $1.6T USD in new revenue and over 9M new jobs by 2026 – study reveals
Just published IDC study reveals that Salesforce economy is set to generate 16 trillion USD in new revenue and over 9 million new jobs by 2026 Read for more awe-inspiring stats
Mon, 20 Sep 2021
Cvent Conference News: September 2021 Product Update Round Up
Mon, 20 Sep 2021
Lokai CEO Steven Izen Says In Sport And Business “It’s All About the People”
When you start a company you think you can do everything in your company better than everyone else observed entrepreneur Steven Izen in a recent episode of Corporate Competitor Podcast Its just not true Izen says that starting two companies taught him that the stronger his team was the more successful and resilient his companies would be We continued to thrive during the Covid pandemic because our sales finance and operations people knew how to adjustIn this podcast the founder of Lokai and Elements uses the handoff of the baton in a relay race to illustrate the classic entrepreneurs journey from running through walls and never taking no for an answer to maturing into a long-term thinking planner whose success depends not only on lots of hard work but also aligning team members around a shared mission and passion for making the world a better placeIzen is in a unique position to speak both to founders and corporate leaders because he currently serves as both He launched Lokai in 2013 as a senior at Cornell and launched Elements six years later Today Lokai products retail at more than 5000 locations in 170 countries Elements products have found a place in Wegmans stores and is being tested at other large chainsListeners are sure to enjoy Izens descriptions of getting his businesses off the ground as well as the differences and similarities of being a founder versus a CEO including How to change from being a founder to a CEO Why the numbers count but arent everything Baking social responsibility into your bottom line The advice Izen gave his fellow Cornell alums about lifeIzen offers a distinctive blend of unwavering confidence and hard-won humility that is sure to inspire and awaken your own creative juices And one things for sure youll never look at a baton handoff in a track relay the same way again ListenYOU WILL LEARN530 How the highs and lows of sport relate to Stevens business700 The lessons from football woven into Stevens journey800 The athletic accomplishment Steven is most proud of1400 His dads impact on his leadership1800 The idea Steven had while studying at Cornell that changed his life1930 Debunking Stevens overnight success2300 The advice Steven gave his fellow Cornell alums about life2900 Lokais partnership with Kyle CarpenterCheck out the full Corporate Competitor Podcast interview archivehttpsnam11safelinksprotectionoutlookcomurlhttps3A2F2Fbitly2F37kSUjIdata047C017Ccjprince40chiefexecutivenet7Cbea0582a872e492becda08d9787a793b7C4d7955266df24a9788152c421914e2637C07C07C6376732897155879457CUnknown7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn03D7C1000sdata4H6r5GIi4lIws2FXARZ3p4iAH8YyuvjvHek48QCI0lAc3Dreserved0 and subscribe to new episodeshttpsnam11safelinksprotectionoutlookcomurlhttp3A2F2Fpodcast-subscribedonyaegercom2Fdata047C017Ccjprince40chiefexecutivenet7Cbea0582a872e492becda08d9787a793b7C4d7955266df24a9788152c421914e2637C07C07C6376732897155978977CUnknown7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn03D7C1000sdataChvaxQYacFe62FXqlO2B6DyjUSmdewDY14tr1y2q48v2BM3Dreserved0The post Lokai CEO Steven Izen Says In Sport And Business Its All About the Peoplehttpschiefexecutivenetlokai-ceo-steven-izen-says-in-sport-and-business-its-all-about-the-people appeared first on ChiefExecutivenethttpschiefexecutivenet
Mon, 20 Sep 2021
How Wedding Pros are Making Guests and Couples Feel Safe Planning Fall and Winter Weddings
While we may have caught a glimpse of what weddings looked like once upon a time pre-pandemic couples everywhere are still rightfully prioritizing guest comfort and safety for their upcoming celebrations Despite vaccination numbers increasing the Delta variant continues to be a cause for concern The fact of the matter is that we shouldnt turn a blind eye to COVID anytime soon and our couples and their guests need our guidance to ensure that they feel safe during the fall and winter event seasonCommon concerns among couplesBeyond the widely known health risks and preventable measures couples are particularly worried about their event becoming a host for COVID whether attendees are vaccinated or notNora Sheils co-founder of Rock Paper Coinhttpsrockpapercoincom and founder of Bridal Blisshttpwwwbridalblisscom notes The Delta Variant has thrown the wedding industry for a loop once again and many that postponed from 2020 into 2021 are still questioning their decisions Couples want to celebrate their day but they want to do it in a way that is safe for all Another concern is ever-changing mandates Some couples have had to change plans more than 5 times including major details like the venue or guest list to minor details like the seating arrangementsLaura Maddox owner of Magnolia Celebrateshttpwwwmagnoliacelebratescom adds Most couples are ensuring that all of their guests are vaccinated This seems to be the biggest concern to date Most clients realize that another shutdown is not likely but they are still wanting to make sure their events are not super spreader events Foodservice safety is still a concern for most clients as well While we know that the virus is not being spread by food in most cases there is still a cleanliness concern for food stations that people are addressing with chef attendants or by opting for a seatedplated dinnerSuggestions you can make to increase comfortThe best-case scenario of course would be that your couples and their guests are all vaccinated accordingly However with mandates varying by state and booster shots now making their way into the conversation its not necessarily going to be as black and whiteThe decision will ultimately be up to the couple but an increasingly popular strategy is requiring a negative COVID test on top of being vaccinated It wont eliminate the possibility entirely of anyone getting sick but it can certainly minimize the odds Luckily more digital health app options such as VOW Digitalhttpsvowdigitalhealthcom Health and CLEAR Health Passhttpswwwclearmecomhealthpass are becoming widely available allowing guests to safely upload the appropriate documents prior to arrivingThomas Waters Senior Event Coordinator and Owner of The Renaissancehttpwwwrenaissancevacom suggests We are strongly suggesting our couples start a wedding website if they dont already have one so they can keep their guests updated in real time to any future potential information they will need to know in regard to mandates postponements and any other timely information I also always suggest allowing us to work up some ideas on lower headcounts just in case If my couple started with 150 guests I will usually offer some suggestions on what the pricing and planning would be like for 125 guests 100 guests and 75 guests Just breaking that barrier down with them to start a conversation about a potentially lower headcount really does help them to start accepting the new increase in casesallseated floorplanhttpswwwallseatedcomwp-contentuploads202109Screen-Shot-2021-09-17-at-20515-PM-e1631906108228pngSee also What Seating Arrangements May Look Like With Social Distancinghttpswwwallseatedcomblogseating-arrangements-with-social-distancing-using-allseated-physical-distancing-toolWhy couples are still decreasing their guest listsThe reality of the situation is that regardless of how many precautions couples may set in place COVID cases are reaching new heights Hospitals are struggling to keep up and we are not fully in the clear when it comes to having the peace of mind that we once hadWaters continues While most of our current couples are wanting their headcounts to stay the same since headcounts are not being restricted as of this time we are seeing the reality that guests friends and families are just not wanting to risk going to a public event Surprisingly we are seeing headcounts go down but not as much as we expected I think each state having differing levels of infection rates has a comfort level on how potential wedding guests may process the theory of safetyAll in all wedding pros have a responsibility to their couples to encourage appropriate health measures and uphold state mandates Couples are going to look to us for advice on keeping everyone safe so its best to be prepared for those conversations and making alternate plansMeghan Ely is the owner of wedding PR and wedding marketing firm OFD Consultinghttpsofdconsultingcom Ely is a sought-after speaker adjunct professor in the field of public relations and a self-professed royal wedding enthusiastThe post How Wedding Pros are Making Guests and Couples Feel Safe Planning Fall and Winter Weddingshttpswwwallseatedcombloghow-wedding-pros-are-making-guests-and-couples-feel-safe-planning-fall-and-winter-weddings appeared first on AllSeatedhttpswwwallseatedcom
Mon, 20 Sep 2021
Study of fungi isolated from pharmaceutical cleanrooms: Types and origins
https1bpblogspotcom-d6UfGCvnr9AYOtgVXeVZ4IAAAAAAAA5K4EC82AG59d9MiYP3WrEg2dw0mJd5rv0MBACLcBGAsYHQs2048fungiairjpgUnderstanding cleanroom microbiota is of importance for microbiologists and quality personnel to assess risks to products and to the environment to propose remediation activities to review changes in trends and to select representative organisms for growth promotion and disinfectant efficacy studies Shifts with the types of organisms may indicate resistant strains problems with cleaning practices and objectionable microorganisms There are few published studies of the typical cleanroom microbiota and extraordinarily little information pertaining to fungi This paper reviews fungi collected across a ten year period from EU GMP Grade C and D cleanrooms from a pharmaceutical facility The paper considers the common types of fungi recovered and discusses their potential origins in relation to people indoor environments and outdoor environments temperate oceanic climate The most common genera of fungi isolates were Aspergillus Candida Cladosporium Fusarium and PenicilliumhttpswwwamazoncomPharmaceutical-Microbiology-Essentials-Quality-Assurancedp0081000227dchild1keywordstimsandleqid1626038378sbookssr1-6linkCodeli3tagpharmigpharma-20linkIdeea35a1383ad66a8023610d1f34208c0languageenUSrefaslissilTim Sandle has written a new peer reviewed paper The reference isSandle T 2021 Study of fungi isolated from pharmaceutical cleanrooms Types and origins European Journal of Parenteral and Pharmaceutical Science 262 httpswwwejppsonlinepostvol26-2-study-of-fungi-isolated-from-pharmaceutical-cleanroomsPosted by Dr Tim Sandle Pharmaceutical Microbiology Resources httpwwwpharmamicroresourcescomPharmaceutical Microbiology c Dr Tim Sandle httpwwwpharmamicroresourcescom
Mon, 20 Sep 2021
Study highlights the usefulness of organoids for basic research into coronaviruses
Researchers from the group of Hans Clevers in collaboration with the group of Bart Haagmans Erasmus MC established an organoid biobank to search for the genes that are essential for the spreading of a SARS-CoV2 infection
Mon, 20 Sep 2021
AI precision medicine accelerates the search for rare disease treatment
AI and precision medicine are both changing drug discovery and development as we know it Precision medicine that is powered by AI stands to be transformative especially for the treatment of rare diseases Elsevier was recently part of a collaboration that sought to demonstrate how AI precision medicine could lead researchers to new treatments for brain tumors fasterHere is an overview of this exciting projectTHE PLAYERS Elsevier and the Sinergia Consortium DMGDIPG Center at University Childrens Hospital Zurich ETH Zurich the Centre for Molecular Medicine Norway and the Open Pediatric Brain Tumor Atlas projectTHE DISEASE TARGET Diffuse intrinsic pontine glioma DIPG a very aggressive type of brain tumor that targets children and currently has no effective treatmentTHE PROJECT Develop an AI disease model that will assist with drug repurposing and support precision medicineTHE PROCESS It started with analyzing OMICs data for DIPG patients using Elseviers Biology Knowledge Graph and complementary software in order to develop a molecular disease model The model was then further built and improved with more data extracted through AI natural language processing and text mining technologies along the wayTHE RESULTS The model was used to identify approved drugs that inhibit the disease mechanism which brought the list of potential drugs down to 212 Further ranking scores were developed to get to the 10 drugs with the most potential for experimental validationWhat did it proveThis project showed how AI NLP and text mining can effectively improve our understanding of rare diseases to find the drug candidates with the most potential which can help researchers focus their efforts on the best leads in the search of treatments for DIPG and other rare diseasesTo go further in-depth and learn more about how the team developed the disease model read this Pharmafield articlehttpspharmafieldcoukindepthhow-ai-precision-medicine-is-helping-find-new-treatments-for-brain-tumors-in-children by Dr Anton Yuryev Professional Services Director at ElsevierYou can also learn more by watching this recent webinarhttpswwwbrighttalkcomwebcast16527489943utmsourcebrighttalk-portalutmmediumwebutmcontentbiology20knowledge20graphutmtermsearch-result-1utmcampaignwebcasts-search-results-feed that Dr Yuryev presented on AI disease modeling
Mon, 20 Sep 2021
Why Are Biofilms a Problem for Pharmaceutical Companies?
https1bpblogspotcom-mUYg9fH9UgYUeag8YZu4IAAAAAAAA528zUOnyi6CNbY8Q049PAiOnWoM154stncVQCLcBGAsYHQs1280Biofilm2jpgImage by Krzysztof A Zacharski CC BY 40 From httpscommonswikimediaorgwindexphpcurid84357356Water is one of the most important components of life but that isnt just limited to humans and other mammals Innumerable forms of life thrive in water and under some conditions that can be dangerous to anyone or anything that takes a sip or uses the substance in otherwise sterile applicationsBy Emily NewtonhttpsrevolutionizedcomThe pharmaceutical industry relies heavily on sterilized water for its operations but large storage containers can serve as an unwanted growth medium for biofilms What are biofilms why are they such a problem for the pharmaceutical industry and what can companies do to prevent their formationhttpswwwamazoncomPharmaceutical-Microbiology-Essentials-Quality-Assurancedp0081000227dchild1keywordstimsandleqid1632082418sbookssr1-3linkCodeli3tagpharmigpharma-20linkIda157203b2881cf5bbca90770e2db938blanguageenUSrefaslissil What Are BiofilmsSurface tension allows bubbles and lightweight bugs to skirt across the surface of a pool of water but it also provides the perfect place for microorganisms to grow Biofilms are communities of microorganisms attached to a surface that play a significant role in the persistence of bacterial infections Theyre often more resistant to antibiotics than planktonic bacteriaBiofilms can float freely on the surface of the water and as they form also become resistant to both external agents and harsh conditions that could damage or kill the bacteria rendering them harmlessProblems Caused by BiofilmsThe biggest problem with biofilms isnt in the water supply its when these bacterial strains start forming colonies in humans Some bacteria such as Burkholderia cepacia and Ralstonia pickettiihttpswwweuropeanpharmaceuticalreviewcomarticle103752pernicious-microorganisms-risks-of-contamination-in-pharma are easily able to proliferate in water sources In 2019 Torrent Pharma Inc had to issue a recall for some of their pharmaceuticals due to microbial contamination with those two bacteria listed above as the prime suspectshttpswwwamazoncomBiocontamination-Control-Pharmaceuticals-Healthcare-Sandledp0128149116dchild1keywordstimsandlebiocontaminationqid1632082444sbookssr1-1linkCodeli3tagpharmigpharma-20linkIdf4b31c4d0baa5f52cd5bcc963b0a23ablanguageenUSrefaslissilOther microorganisms such as Legionella and Pseudomonashttpsmicromanagementinccomservices are almost always present in water systems though the concentrations are generally low enough that they are easy to manage and dont pose any health risks to anyone consuming the water or using it for different tasksGetting rid of these colonies in pipes or storage tanks is relatively easy Getting rid of them once they infect a human being is nearly impossible partially because the amount of antibacterial agents necessary to treat them would be harmful to the patient and partially because theyre most dangerous in immunocompromised patients Biofilm colonies of those two bacteria are often found in cystic fibrosis patientshttpswwwncbinlmnihgovpmcarticlesPMC2542406 contributing to the conditions chronic statusThe challenge here lies not in elimination from tanks but in detection in the first place Treating water supplies with antibacterial agents on a regular basis could help prevent the formation of biofilms but it could also contribute to the creation of superbugs that would be even harder to get rid ofPreventing Biofilm in Pharmaceutical Storage TanksPreventing biofilm formation in pharmaceutical settings isnt always easy but there are steps that companies can take to ensure there is no microbial contamination in their productsStart by keeping things moving The global pharmaceutical supply chain has taken a hit in 2020 and 2021 as things like the COVID-19 pandemic and Brexithttpsrevolutionizedcomresilience-for-pharmaceutical-supply-chains changed the way the world interacted with one another Some supply chains couldnt keep up with the demand while others found themselves floundering with production lines sitting idle as they waited for orders to arrive or workers sent home because of the pandemic to return and resume operations Tanks and storage facilities allowed to sit idle increase the chances of biofilm development Keeping the water moving can reduce these chances but it isnt a foolproof method so other tools will also be necessaryHot storage can prevent biofilms from forming in the first place by creating an inhospitable environment for the bacteria Temperatures used for food pasteurization up to 120C 248F are usually sufficient to prevent the formation of the biofilms though steps will need to be taken to prevent evaporation as the water is treated or stored above its natural boiling point There will also need to be steps taken to reduce the water temperature when the water is neededDry steam is emerging as a tool for killing developed biofilms that might be resistant to other treatments One study found that a three-second steam treatmenthttpswwwajicjournalorgarticleS0196-65531101317-4fulltext killed exposed biofilms 9995 of the time For comparison a similar treatment with 10-ppm bleach sodium hypochlorite takes 10-20 minutes to achieve the same resultsFiltering the water through silver-impregnated systems can also help prevent biofilm formation due to the silvers naturally antibacterial and antimicrobial properties This hasnt been attempted in the pharmaceutical industry but the technology has shown promise in communities where high bacterial concentrationshttpswwwncbinlmnihgovpmcarticlesPMC5886460in drinking water were putting health at riskBiofilms Are Dangerous but PreventableBiofilms can be dangerous especially to immunocompromised individuals but they are also preventable These bacterial colonies can spring up in as little as 24 hours Detection and prevention are the two most important keys though there are remedies available if biofilm problems are detectedThe easiest way to prevent them is to keep things moving If that isnt an option high temperatures dry steam and even things like silver nanoparticles can help prevent biofilm formation and keep everyone safe and healthyPharmaceutical Microbiology Resources httpwwwpharmamicroresourcescomPharmaceutical Microbiology c Dr Tim Sandle httpwwwpharmamicroresourcescom
Sun, 19 Sep 2021
Stop Checking Compliance Boxes: Start Measuring Proficiency to Drive Business Results
It’s standard in corporate learning models to use LMSs, but these learning systems weren’t designed for skill-building. And traditionally, industry-wide success with those systems has been defined by course completion metrics rather than proficiency. This doesn't truly demonstrate L&D’s business value to managers and executives. Corporate training and development is moving away from traditional methods and towards a microlearning strategy that empowers learning professionals with the tools to efficiently upskill and reskill a workforce and deliver business results. This white paper will go in depth on the benefits of modernizing your learning approach, with insights on how microlearning courses and its analytics help employees acquire important new skills and knowledge that align with business objectives.
Tue, 14 Sep 2021
6 Mid-Autumn Festival greetings to share with your co-workers
The Human Resources Online team wishes you all a happy and wonderful Mid-Autumn Moon Festival
Mon, 20 Sep 2021
5 Benefits of Video Conferencing for HR
If the year 2020 taught us anything its that a remote workforce is a productive workforcehttpshrdailyadvisorblrcom20180711can-allowing-remote-work-improve-productivity Though remote work used to be a rare occurrence companies are beginning to see the benefits of having their teams work and operate from home During this transition the emergence of video conferencing has been the biggest game-changer of allhttpsnewsblrcomappuploadssites3202102boringvideoconferencejpgsource Golubovy shutterstockAs a human resources employee video conferencing should become your new best friend The advantages of this platform are huge from the ability to reach out to candidates around the world to the chance to help employees accessibility issues video conferencing can do it all Lets look at some advantages of this tech and how you can start implementing it into your day-to-day operations1 Personal ConnectionThe human resources departmenthttpswwwlucidchartcomblogguide-to-the-human-resources-career-path is composed of many different positions and they can all benefit from video even when your team is only discussing topics amongst themselves From assistants who respond directly to employee questions to managers who handle all the tiny details everyone on the team can use video to communicate clearly and efficiently at the touch of a buttonThe greatest benefit of video conferencing software is the ability to communicate and meet in person even if were far apart By connecting over video you can share all necessary details with your coworkers without having to go back and forth in emails or direct messages Plus the human connection is essential when were all isolated and working from home2 Easier InterviewsVideo conferencing allows you to interview candidates with considerably less effort than it used to take In the past in-person interviews severely limited the number of candidates a company could consider Now with widely accepted remote options employees can interview and work from almost anywhere This helps you find the perfect fit for any position Furthermore HR can send recorded videos of interviews to other decision-makers within the company for review3 Reduce CostsWhile interviewing is easier with video conferencing its also less expensive Not only do employees not need to pay for travel there are also fewer expenses when there is no physical office lighting utilities rent etcIn the past when interviewing for high-ranking positions many companies would fly in candidates put them up in hotels provide rental cars and then pay to send them home That too is a thing of the past and the savings can be exponential4 Mental Health ConsiderationsWhile the interviewing aspect is great video conferencing can also help with the needs of your current employees especially when your department is working to improve employees mental healthhttpsoitchaucombloghow-your-hr-department-can-improve-employee-mental-health The ability to speak to HR or anyone at the office without having to be physically present creates more opportunities to allow employees to work from home and work flexible schedulesWith COVID-19 still a factor many working parents are dealing with extra responsibilities including caring for their kids and homeschooling If HR can provide the chance for employees to start later in the day so they can take care of their kids and still be face to face for an important meeting via video conferencing it will make a big difference in your employees life and they will truly appreciate the gestureIn addition to flex time video conferencing allows HR representatives to administer mental health training sessions wherever the employee may be which could be an instrumental factor of your employee retention strategy5 Easier PresentationsOn the topic of presentations HR can also use video conferencing software to schedule high-quality webinars for management or staff In addition to showing your face during the meeting you can also utilize the benefits of screen-sharingJust about every video conferencing tool has a screen-sharing option and it allows you to show the content on your screen to your audience in real-time Slide show presentations are particularly powerful in this medium and you can also record your screen during the show so your webinar can be watched again at a later time by any employees who missed itConclusionIn the end its clear to see that video software is a true game-changer for HR and the world of business in general Consider implementing this technology today and your internal team and your company will be better for itThe post 5 Benefits of Video Conferencing for HRhttpshrdailyadvisorblrcom202109205-benefits-of-video-conferencing-for-hr appeared first on HR Daily Advisorhttpshrdailyadvisorblrcom
Mon, 20 Sep 2021
Diversity Takes Many Forms: Making Progress Through Understanding and Inclusion
Successful diversity equity and inclusion leadership requires the same kinds of leadership skills that make one successful in any corporate leadership role whether that be operations finance marketing or anything else But it also requires a solid understanding and knowledge of the underlying subject matter Working in a relatively new area of corporate focus DEI professionals often rely on academic studies to supplement the limited availability of established real-world experience as they pursue DEI efforts in a corporate settingdr lusharon wiley innisfreehttpsnewsblrcomappuploadssites3202109Dr-Wiley-Headshot-2jpgFor this feature we spoke to someone who has a great combination of both real world DEI experience as well as years of academic muscle in the study and science of diversity equity and inclusionDr Lusharon Wileyhttpsinnisfreehotelscombloglusharon-wiley has over two decades of experience as a successful manager and leader in higher education As Director of Culture at Innisfree Hotels a Florida-based hotel management marketing and development company she has the important job of managing the companys culture practices and providing expertise and support in the areas of employee relations employee engagement and retention diversity and inclusion performance management and HR compliancePerspective Frames and LensesOne of the challenges so many organizations face when it comes to their diversity equity and inclusion efforts is that theyre bound by the implicit biases and traditional ways of viewing the world that have caused the very workplace disparities and lack of diversity theyre trying to address Its difficult for companieslike peopleto recognize their own distorted perspectives and appreciate that how they frame conversations around DEI as well as the lenses they look through need to be critically evaluated This is why so many companies look externally for their DEI executive leadersDr Wiley experienced the challenges of distorted perspectives and framing firsthand at an early point in her career My first professional job was in economic services where I determined applicants eligibility for state public assistance she explains It struck me that many of the employees seemed to have an attitude of superiority toward the customers we served I remember thinking that we are not better than its simply that our fates our lives were being lived out differently This greater than less than dichotomy continued to be a focus for me as I moved to different jobs and communities across AmericaWiley says that it was during her employment in higher education that her focus on diversity and inclusion became clearer I wanted to help ensure that students had the opportunity to explore and appreciate differences while providing a platform for discourse about topics that are often avoided or not authentically discussed she says It was important for students to know that all people matter and that not feeling valued hurtsTackling Diversity Equity and Inclusion in Higher EducationInstitutions of higher education like all long-standing institutions are steeped in tradition customs and habits But even this seemingly liberal environment so accustomed to the impacts of change and the value of diverse thoughts and viewpoints can struggle to adequately foster strong DEIDuring her time working in higher education Dr Wiley sought to promote DEI by creating structure and organizational networks features that could become part of the institution itself As I continued to pursue the path of inclusion and diversity I started programs at my university that provided students with opportunities for campus and community involvement she explains In addition to my assigned job I carved out an area on inclusion that would eventually become Inclusion Services In that environment I started a group called Common Ground The groups purpose she says was to train students and staff to appreciate differences while providing them the skills needed to train othersIn addition to Common Ground Wiley started a series called Inclusion Spotlight This initiative focused on diverse people in our community whose jobs or experiences were unusual she says These discussions with people in our neighborhood helped to expand the worldview of students and faculty alike and added to our understanding of othersThe success of her higher education initiatives along with a doctorate in Diversity Studies prompted Wiley to want to do moreand to know more I became more active in my community my worldview was expanding she says When the position of Director of Culture became available at Innisfree Hotels it seemed a natural place for me Who knew there was a company in my community with a focus on inclusion diversity and equity I applied for the position and to my good fortune was hiredBuilding on a Strong FoundationDr Wiley was fortunate to engage with a company that already had a solid foundation to build upon There was a wonderful person already working with Innisfree by the name of Jack Guillebeaux she says He and company owner and founder Julian MacQueen already had in place the foundation for the Innisfree culture There were culture tools the Cooperative Mode and training on diversity and inclusion called Genesis Building upon this foundation implementing an onboarding process and providing need-specific group facilitation while focusing on equity and accessibility are some areas that are being expanded to ensure that the Innisfree culture is consistently reinforced and sustainedInclusion through SharingInclusion cant truly work unless those the organization is seeking to include feel comfortable sharing who they are Dr Wiley says the goal at Innisfree Hotels is to make every team member feel valued accepted and respected It is not enough for team members to be at the table she explains they must feel that the dish they bring to the table will be tastedeven if the dish is not the usual fare All too often people with great talent leave a company because they feel excluded and unheardOne of the tools Innisfree Hotels utilizes is inviting and embracing non-conventional thinking Deep diving into conversations that may become intense requires a mindset that is ready to embrace change even amid the messiness that it might take to get to the next level It is often in this place of discomfort and ambiguity that creativity can flourish Dr Wiley explains We recognize that varying viewpoints and perspectives can result in something that is transformational for the companyOne of the many tools Innisfree uses to foster this culture of sharing and inclusiveness is the check-in which provides each team member the opportunity to share whats on their minds and how they are doing During this sacred time of sharing team members might share their concerns about a child who is ill an upcoming graduation or a fun experience Wiley explains This is a time where we stop to say YOU matter and we want to know how you are doingAnother tool Wiley and Innisfree rely on is their Genesis training which includes their Cooperative Mode tools and is provided to all team members focuses on how to have tough conversations how to foster and sustain an inclusive work environment barriers to communication in the workplace implicit bias and other topics These times of intense conversation are key to understanding others traditions experiences and perspectives Wiley says In these shared moments community is built Ongoing training is key to sustaining a culture of inclusionDiversity equity and inclusionwhen applied in the corporate worldnecessarily rely on business concepts to pursue business goals At the same time the relative newness of this business function means that academic research and tools can provide a useful supplement to a relative dearth of collective real-world experienceFortunately for Dr Wileyand Innisfree Hotelsshe comes to the table with a solid background in both academia and real-world experienceThe post Diversity Takes Many Forms Making Progress Through Understanding and Inclusionhttpshrdailyadvisorblrcom20210920diversity-takes-many-forms-making-progress-through-understanding-and-inclusion appeared first on HR Daily Advisorhttpshrdailyadvisorblrcom
Mon, 20 Sep 2021
Good ad or bad ad? FDA quiz reminds docs about its Bad Ad program to police problematic advertising
Good ad or bad ad FDA quiz reminds docs about its Bad Ad program to police problematic advertising bbulik Mon 09202021 - 1206 httpswwwaddtoanycomshareurlhttps3A2F2Fwwwfiercepharmacom2Fmarketing2Fgood-ad-or-bad-ad-fda-quiz-reminds-docs-about-its-bad-ad-program-to-police-problematictitleGood20ad20or20bad20ad3F20FDA20quiz20reminds20docs20about20its20Bad20Ad20program20to20police20problematic20advertising
Mon, 20 Sep 2021
Overnight Health Care — Presented by Indivior —Pfizer: COVID-19 vaccine safe for young kids
Welcome to Mondays Overnight Health Care where were following the latest moves on policy and news affecting your health Subscribe here thehillcomnewsletter-signup Ben Jerrys has created a new flavor to support Rep Cori Bushs D
Mon, 20 Sep 2021
US COVID-19 death toll surpasses that of 1918 pandemic
The US death toll from COVID-19 has surpassed that of the 1918 flu pandemic according to a tracker from Johns Hopkins University highlighting the extraordinary damage incurred by the current virusThe US has passed 675000 deaths the
Mon, 20 Sep 2021
LA County reports first West Nile death of the year
The Los Angeles County Department of Public Health has confirmed its first West Nile virus death this year To the family and friends feeling the sorrow of losing this person due to WNV we send you our deepest sympathies Los Angeles
Mon, 20 Sep 2021
RNA-targeting enzyme expands the CRISPR toolkit
Researchers at MITs McGovern Institute for Brain Research have discovered a bacterial enzyme that they say could expand scientists CRISPR toolkit making it easy to cut and edit RNA with the kind of precision that until now has only been available for DNA editing The enzyme called Cas7-11 modifies RNA targets without harming cells suggesting that in addition to being a valuable research tool it provides a fertile platform for therapeutic applications
Mon, 20 Sep 2021
ESMO: Syros targets KRAS-mutant cancer as CDK7 inhibitor shows early promise
ESMO Syros targets KRAS-mutant cancer as CDK7 inhibitor shows early promise aliu Mon 09202021 - 1025 httpswwwaddtoanycomshareurlhttps3A2F2Fwwwfiercebiotechcom2Fresearch2Fsyros-targets-kras-mutant-cancer-as-cdk7-inhibitor-shows-early-promisetitleESMO3A20Syros20targets20KRAS-mutant20cancer20as20CDK720inhibitor20shows20early20promise20
Mon, 20 Sep 2021
Workshop and lecture on generic portfolio management
Ill be leading a workshop on generic portfolio management and also giving a talk at the 14th annual Marcus Evans event on Portfolio Planning and Partnerships for Generics The eventThe post Workshop and lecture on generic portfolio managementhttpswwwdrugpatentwatchcomblogworkshop-and-lecture-on-generic-portfolio-management appeared first on DrugPatentWatch - Make Better DecisionshttpswwwdrugpatentwatchcomblogThe post Workshop and lecture on generic portfolio managementhttpswwwdrugpatentwatchcomblogworkshop-and-lecture-on-generic-portfolio-management appeared first on Biotechbloghttpswwwbiotechblogcom
Mon, 20 Sep 2021
Cristae-dependent quality control of the mitochondrial genome
Mitochondrial genomes MtDNA comprise essential subunits of the mitochondrial respiratory chain therefore mutations in mtDNA can reduce cellular energy support and cause mitochondrial diseases Researchers seek to understand how cells can secure the integrity of mtDNA across generations In a new study now published on Science Advances Christopher Jakubke and an international research team in biology and biophysics demonstrated how single-celled yeast Saccharomyces cerevisiae could intracellularly distinguish between functional and defective mtDNA The outcomes of the research can support a model that shows how the proximity between mtDNA and the proteins it encodes can create a sphere of influence to understand the functional mtDNA in cells
Mon, 20 Sep 2021
3D Microscopy of Whole Organs with Micrometer Detail
A team of scientists at Ume University in Sweden came up with a way to create complex 3D maps of whole organs in incredible detail The approach involves embedding a whole organ in agarose a stiff gel matrix and then using this support matrix to section the tissue into cm3 chunksThese chunks are the perfect size for fluorescent antibody labeling of specific cell types and subsequent deep tissue imaging using a technique such as optical projection tomography Once the chunks are labeled and imaged it is possible to stitch the images together on a computer to create a 3D map of the entire organThe researchers hope that the technique could reveal previously unobservable changes in diseased organs and it allows them to track cellular changes at a whole-organ level This method may contribute to an advanced understanding of how cellular changes are related to different disease conditions said Ulf Ahlgren one of the creators of the new method in a press releaseSo far the researcher have used the technique to study the pancreas using organs from human volunteers The team compared the distribution of the hundreds of thousands of islets of Langerhans within pancreases from healthy volunteers and those with type 2 diabetes They identified previously unknown areas that have a very high islet density something that may be useful in improving islet transplantation techniquesIllustration of how a pancreas can be divided into smaller parts that are labelled depending on their specific cell types using the insulin-coloured Islets of Langerhans The parts can then be pieced together using a computer as a three-dimensional jigsaw puzzle to recreate the entire human organ Image Max Hahn Ulf AhlgrenBesides using the new method to study diabetes it can also improve understanding of other pancreatic diseases not least pancreatic cancers and we have initiated collaborations with clinical researchers in Ume to look into that said Ahlgren But the technology itself should be possible to use to study other organs and diseases in similar ways since it enables the study of where cellular changes take place in a full organ context their amount and relationship to nearby tissues and cell typesStudy in Communications Biology 3D imaging of human organs with micrometer resolution applied to the endocrine pancreashttpswwwnaturecomarticless42003-021-02589-xVia Ume Universityhttpswwwumuseennewsny-metod-mojliggor-detaljstudier-av-manskliga-organ-i-3d10872495
Mon, 20 Sep 2021
3D-Printed Origami Tube for Low-Cost Ventilators
Researchers at Simon Fraser University in Canada have developed a low-cost portable ventilator that uses a 3D-printed origami tube rather than a conventional airbag The volume of the tube can be modified by changing the angles in the origami folding plates As up to 95 of the components of the ventilator are 3D printable the device can be created for approximately 200 compared with approximately 2000 for existing portable ventilatorsVentilators have been a key tool during the COVID-19 pandemic and shortages have inspired a variety of makeshift and innovative devices that have helped to save lives While the worst effects of COVID-19 have been blunted by successful vaccination campaigns in many countries millions of people do not yet have access to the vaccines and the virus continues causing problemsIn many developing nations lack of access to vaccines healthcare facilities and equipment could make the difference between life and death during the pandemic There is an ongoing need for low-cost and portable medical equipment to treat COVID-19 patients in such regions particularly in rural and remote locationsWhile this latest technology is designed to be low-cost it is far from makeshift employing 3D printing and a unique origami design to create a small and portable ventilator In the place of a simple bag the ventilator includes a 3D printed origami tube in which origami folding plates interlock to form a tube that is smaller and stronger than the equivalent component in a conventional ventilatorDuring operation the tube is contracted to assist in breathing As with so many devices intended for low-resource use 3D printing was the key to the low cost of the technology In our portable origami ventilator more than 95 per cent of components can be 3D printable thats why it is really cost-efficient said Woo Soo Kim one of the developers of the new technology in a press releas Other portable ventilators can cost over 2000 but our 3D-printed ventilator can be produced for about 200The researchers hope that the technology could assist in low-resource or remote regions where healthcare resources are scarce They have partnered with a ventilator manufacturer with a view to scaling up production of the devicesStudy in Flexible and Printed Electronics 3D architectured air sensing tubes for a portable mechanical ventilatorhttpsiopscienceioporgarticle1010882058-8585ac1fd6Via Simon Fraser Universityhttpswwwsfucauniversity-communicationsissues-experts202109technology-takes-the-art-of-origami-into-the-fight-against-covidhtml
Mon, 20 Sep 2021
A Look at the Australian Medtech Market
Australia can learn 3 important lessons from the United States when it comes to medtech startup support
Mon, 20 Sep 2021
Medtronic's Latest Recall Linked to 2 Deaths, 10 Serious Injuries
The company is recalling thousands of embolization devices because there is a risk of the delivery systems wires and tubes fracturing and breaking off during placement retrieval or movement of the device
Mon, 20 Sep 2021
Food and Culture
Is this the next Game of Thrones?
Why Apple TV show Foundation could be the TV epic that weve been waiting for
Mon, 20 Sep 2021
square grill pan
Home Cooks Are Ditching Le Creuset for This Beloved Nonstick Brandand You Can Snag Its Grill Pan for Just 60 at Amazon
Mon, 20 Sep 2021
Health & Fitness
11 Best Latinx Beauty Brands To Shop This Month—And Always
Its Hispanic Heritage Monthhttpswwwwellandgoodcomlatinx-owned-wellness-brands from September 15 through October 15 and while the term Hispanic is generally viewed as a problematic way of lumping tens of millions of individuals under one label this month at the very least offers an occasion for drawing attention to those in the community With that disclaimer out of the way its time to celebrate LatinxHispanic individuals making waves sometimes literally in the beauty industry via a roundup of the best Latinx beauty brandsThere are many many beauty brands created by Latinx individuals from countries all over the world so narrowing it down to just a few is a tough task and this list is by no means a comprehensive accounting of them all Nevertheless it includes brands that have hooked us to their products charmed us with their branding and goals andor done all of the aboveBelow find 11 products from some of the best Latinx beauty brands around along with a little background on the faces behind the vanity table so to speak11 products from the best Latinx beauty brands including makeup skin care and hair care companies well be shopping foreverTIPWith the WellGood SHOPhttpsshopwellandgoodcom you can now add products to your cart right from this article page Just click on the product below and more details will pop up in a new window Hit add to cart and voila Thats it As you read more SHOP articles you can keep adding products to your cart and check out when youre ready look for the cart icon on the right side of your screenjoanna vargashttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckid15v0w000i110mewtacjj0bonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrue httpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckid15v0w000i110mewtacjj0bonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrueJoanna Vargas Forever Glow Anti-Aging Face Mask 7500Mexican-American aesthetician Joanna Vargashttpswwwwellandgoodcomjoanna-vargas-advice-water-temperature is the go-to gal for many a glow-y A-list celeb Shes known for melding skin care technology and product into treatments that offer legit results and yet somehow her off-the-shelf products manage to package that in-person magic for those who cant make it to her NYC- or LA-based spas Shes been using plant-based ingredients since long before it was the trend too These masks from the line are a personal favoritetheyre amazing hydrators pumped full of antioxidants to soothe and nourish the skinShop Nowhttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckid15v0w000i110mewtacjj0bonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltruechillhousehttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductcks8kn9hb00a21sp5dbh4cot8bonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrue httpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductcks8kn9hb00a21sp5dbh4cot8bonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrueChillhouse Chill Tips Reusable Press-on Nails in Editor-In-Chill 1600Chillhouse founder Cyndi Ramirez-Fultonhttpswwwwellandgoodcomcyndi-ramirez-fulton-beauty-vips-favorite-beauty-products launched her flagship spa in Manhattans SoHo neighborhood after realizing existing spa options didnt really speak to her or others in her demographic it was difficult to find quality services in a chic environment without an untenable price tag Shes since made a splash with a product line most famous for its clutch-in-a-pandemic press-on nails embossed with cool millennial-y patterns The brand also makes all-natural face and body oils that aim to simplify your beauty regimen and elevate your mood through carefully-crafted scentsShop Nowhttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductcks8kn9hb00a21sp5dbh4cot8bonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrueTata Harperhttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkejk0nx0l7i1caq6frcbgr1bonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrue httpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkejk0nx0l7i1caq6frcbgr1bonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrueTata Harper Resurfacing Mask 6500Colombia native Tata Harper is a green beauty pioneer who was inspired to launch clean skin care after learning about the potential harms of synthetic chemicals during a family members battle with cancer But she didnt take the easy route by creating simple oils made from one or two ingredients Instead Tata Harpers products are complex innovative luxurious andmost importantlyeffective AF Everything is made from farm to bottle on the Vermont farm where Harper lives too This dermatologist-approved maskhttpswwwwellandgoodcombeauty-products-worth-the-splurge-saks-fifth-avenue is a hero of the line which relies on pomegranate enzymes to hydrate the skin and white willow bark to diminish both wrinkles and poresShop Nowhttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkejk0nx0l7i1caq6frcbgr1bonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltruebeautyblenderhttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkemttni0t3d1dai03p5d6l5bonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrue httpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkemttni0t3d1dai03p5d6l5bonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrueOriginal Makeup Sponge Applicator 2000BeautyBlender founder Rea Ann Silva was one of the first makeup artists to work on a high-definition TV show you know the ones that make everyone look too real and so her custom-made now-famous sponge was born from the challenge of trying to make actors skin look perfect in those all-too-revealing conditions When her sponges began to go missing from set she realized she was on to something and set to work launching them commercially They are now ubiquitous and Silva has since launched a foundation in 40 shades so that modern women of color dont have to do the most to bootleg hues that match their skin tone as she did for years to service her non-white clients The BeautyBlender line now also offers primers highlighters and moreShop Nowhttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkemttni0t3d1dai03p5d6l5bonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltruerare beauty linerhttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkdqicht01hs1c1k7izc9qdibonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrue httpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkdqicht01hs1c1k7izc9qdibonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrueRare Beauty Perfect Strokes Matte Liquid Liner 1900This companys founder likely needs no introduction unless youve been living under a rock for the last IDK 15 years Rare Beauty is Selena Gomezs brand and like Rihannas Fenty its not just a celebrity vanity project in fact its products are actuallygreat The line consists of a weightless serum foundation that comes in 48 shades a fan-favorite melt-into-your-skin cream blush a liquid eyeliner I personally swear by and much much more The company also offers mental health resources through its website and donates a percentage of its proceeds to efforts to increase access to mental health servicesShop Nowhttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkdqicht01hs1c1k7izc9qdibonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltruesigna brush sethttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckoxlo9bc0x461r3ae5to8viqbonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrue httpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckoxlo9bc0x461r3ae5to8viqbonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrueSigma Essential Trio Brush Set 2900Sigma Beauty was founded by Brazilian natives Simone Xavier and Rene Xavier Filho and it launched with a single makeup brush in 2009 That product quickly became a must-have and the line has since expanded into additional brushes as well as a full makeup offering Now the company owns over 60 patents on their products which speaks to the innovative nature of their creations Trust me theres almost no reason to use any other brush but SigmasShop Nowhttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckoxlo9bc0x461r3ae5to8viqbonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrueartist couturehttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkdq2w0n00cm1cyic13q4r7lbonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrue httpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkdq2w0n00cm1cyic13q4r7lbonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrueArtist Couture Diamond Glow Powde 2700Artist Couture is the creation of beauty influencer and professional makeup artist Angel Merinoor Mac Daddyy as he is known online Merino is not exactly famous for an understated aesthetic but his products work as well for those who want to look au naturel as they do for those who live to stand out in a crowd The line is extensive but its hero product is the Diamond Glow Powder a loose powder highlighter that adds an otherworldly shimmer wherever eg cheeks eyes you want to shineShop Nowhttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkdq2w0n00cm1cyic13q4r7lbonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltruecelestial storm palettehttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkzq1z9300br122u1kz12he6bonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrue httpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkzq1z9300br122u1kz12he6bonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrueDominique Cosmetics Celestial Storm Palette 2200Dominque Cosmetics is another line created by a beauty influencer in this case the undeniably gorgeous Christen Dominique She got into makeup at the age of 14 when she found that concealer could help erase the dark circles that were her greatest source of self-consciousness After a long journey through the vlogosphere she decided to launch her own line of multi-tasking products that offer luxury results without an out-of-reach price tag Her pigmented eyeshadows and matte lipsticks are fan-favorites though you really cant go wrong with any of the lines extensive offeringsShop Nowhttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkzq1z9300br122u1kz12he6bonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltruemelthttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkmapew805oo1czqepfsb0mibonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrue httpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkmapew805oo1czqepfsb0mibonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrueMelt Cosmetics Amor Eterno Liquid Lipstick 2500Melt Cosmetics began in 2012 with the simple realization that it was difficult to find matte lipsticks in boldeven crazycolors think hot pinks purples and more Founders Lora Arellano and Dana Bomar set out to fill this void quickly thereafter and fill it they didinarguably they launched the bold lip trend still popular despite masking to this day Having experienced phenomenal success with their initial lip products the two makeup experts have since expanded to a fuller line of cosmetics including blushes highlighters eye pencils and moreShop Nowhttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckkmapew805oo1czqepfsb0mibonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrueshocks of lovehttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckl9q9h1c001i12b8amstbn5dbonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrue httpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckl9q9h1c001i12b8amstbn5dbonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrueShocks of Love Loving Care Vitality Scent Ritual 6500Shocks of Lovecreated by aromatherapist and self-taught perfumer Juan Felipe Rendonexists at the intersection of beauty and wellness Its scent rituals read aromatherapy products are handcrafted responsibly-sourced and certified organic Next the company plans to launch perfumes designed in collaboration with various artists And if you love a brand with a little heart behind it you should know that Rendon donates five percent of profits to an organization called Activation Residency which is a Black-led artist residency designed for Black Brown Indigenous Trans and Queer individualsShop Nowhttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckl9q9h1c001i12b8amstbn5dbonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltruehttpswwwwellandgoodcombest-latinx-beauty-brandsbonsaiproductckker5bpz13wx1c9x6b5y8u9cbonsaiRedirecthttps253A252F252Fwwwwellandgoodcom252Fbest-latinx-beauty-brands252FbonsaiSourcelinkbonsaiTypelinksisExternaltrue
Mon, 20 Sep 2021
The 2021 Dodge Hellcat Can Drain Its Fuel Tank in 11 Minutes
A funny thing happened when the pandemichttpswwwmensjournalcomtraveldodge-airport-road-trip-uncrowded-places hit and the economy went into a free fall Cars didnt stop sellingespecially fast oneshttpswwwmensjournalcomgearsexiest-hypercars-from-manhattan-motorcars-showcase-mens-journal Turns out contemplating mortality meant for many of us enjoying the visceral pleasures available to us while we still could For some that meant going out and buying the 2021 Dodge Charger Hellcat Redeye WidebodyAfter driving one I tip my dopamine-soaked cap to those buyers On an emotional scale of 1 to 10 the fastest mass-produced sedan in the world is somewhere in near-earth orbit Jeff Bezos unloaded much more than the 90050 sticker price on our test car to get thereDodge Hellcat reimaginedThe Hellcat at hand represents another chapter in an ongoing story When Dodge unleashed the Hellcat name back in 2014 with the first iteration of its 62-liter V-8-powered supercharged monster it was part of a bid to leave boring cars behind ceding the everyday stuff to other brands Apparently selling a 700-plus-horsepower machine to the masses was such a wild idea that it worked Over 50000 Hellcats have found driveways thus far helped in part by hip-hop lyrics its shown up in bars from Chief Keef Quavo Lil Baby and many moreWhite and black sport car racing toward cameraCourtesy ImageExterior of 2022 Nissan Frontier truck with mountains in the backgroundhttpswwwmensjournalcomgearreview-2022-nissan-frontier-is-big-on-off-road-comfort-mens-journalThe 2022 Nissan Frontier Is a Case Study in Beauty and Brawnhttpswwwmensjournalcomgearreview-2022-nissan-frontier-is-big-on-off-road-comfort-mens-journal Read articlehttpswwwmensjournalcomgearreview-2022-nissan-frontier-is-big-on-off-road-comfort-mens-journalOur tester made it easy to see why the things a pop culture hit It wore a Go Mango paint job which is a kind of orange solar-plasma blast and came with a speedometer that tops out at 220 mph It looks unsubtle and drives no differently The freeway starts to feel like a strobing video game as the high whine of its supercharger adds hair-on-fire flare A quarter mile passes by in the mid-ten seconds You become friends with the 14-inch Brembo brakes Hilariously a car seat fits in back just finedownload-1httpswwwmensjournalcomentertainmentansel-elgort-talks-fast-cars-rock-climbsAnsel Elgort Talks Fast Cars How He Got Into Climbing and Morehttpswwwmensjournalcomentertainmentansel-elgort-talks-fast-cars-rock-climbs Read articlehttpswwwmensjournalcomentertainmentansel-elgort-talks-fast-cars-rock-climbsBut heres the thinghavent electric cars like the 1020-horsepower Tesla Model S Plaid turned the fuel-sucking Hellcat into a dinosaur I called Dodge CEO Tim Kuniskis to ask He didnt seem worriedSport car engineCourtesy ImageThe technology of electrics is amazingyou can have better control of acceleration and traction you have instantaneous power he said Every mainstream product is going to go toward electrification And when they do and we have economies of scale that make it more affordable its going to be the muscle car war all over againSo folks the Hellcat might have a quieter even faster electric future For now enjoy this late-stage internal-combustion masterworkAt wide-open throttle Dodge says the Charger Hellcat Redeye can drain its fuel tank in 11 minutes using two dual-stage fuel pumps Were here for a good time not a long time rightGet ithttpswwwdodgecomchargersrthtml
Mon, 20 Sep 2021
Have a Laugh
Alicia Vikander
Alicia Vikander Slimjpghttpsopenspotifycomshow6kAsbP8pxwaU2kPibKTuHEAlicia Vikander Ex Machina The Green Knight Blue Bayou is an Academy Award-winning Swedish actress Alicia joins the Armchair Expert to discuss how her ballet training translated to her film career moving to Stockholm at 15 from a small town and her experience on the set of Ex Machina Alicia and Dax talk about the difference between Swedish and American cultures how we overuse the phrase I love you and how she was terrified about doing an American accent in her new movie Alicia explains how her dad can have deep conversations with strangers how New Orleans is one of her new favorite cities and that she hopes to have some comedy roles in the futureView fullsize DaxShepard-01jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851632100833931-OSOXRRWBU4AAOWAX6ZCFDaxShepard-01jpg View fullsize AliciaVikanderScreenshot-04jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851632100824286-L3JHUGRCG7I4DUQ3S1XQAliciaVikanderScreenshot-04jpg View fullsize MonicaPadman-04jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851632100876071-C5BCC58XGYYUA8CQ2POTMonicaPadman-04jpg View fullsize DaxShepardMonicaPadman-10jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851632100856133-UBL0K3T81UN1ER9ZG25VDaxShepard26MonicaPadman-10jpg View fullsize AliciaVikander-1jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851632100830438-MVC2HI634EFO53UER19PAliciaVikander-1jpg View fullsize DaxShepardMonicaPadman-02jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851632100849454-DJRFQA3JL122CNAIKC6LDaxShepard26MonicaPadman-02jpg View fullsize JessRowland-01jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851632100870069-OWNNDTG5RNZTQL9HBCTGJessRowland-01jpg View fullsize DaxShepard-04jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851632100840068-31R4DSY0PMBEVD09EO8NDaxShepard-04jpg View fullsize JessRowland-02jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851632100870135-MGQWILLSCLAR9YYD68NCJessRowland-02jpgArmchair Expert armchairexppodhttpswwwinstagramcomarmchairexppodDax Shepard daxshepardhttpswwwinstagramcomdaxshepardCreated Produced by Dax Shepardhttpsinstagramcomdaxshepard Monica Padmanhttpswwwinstagramcommlpadman Rob HolyszhttpswwwinstagramcomwobbywobHosted by Dax ShepardEdited by Monica Padman Laura MosesMixed Mastered by Billy Klein
Mon, 20 Sep 2021
Dr. Harold S. Koplewicz
Harold Koplewicz Slimjpghttpsopenspotifycomshow6kAsbP8pxwaU2kPibKTuHEDr Harold S Koplewicz The Scaffold Effect is a psychiatrist and founder of the Child Mind Institute Dr Koplewicz joins the Armchair Expert to discuss child mental health advocacy the controversy of medication as treatment for children and how he deals with parents who dont believe in child psychiatry Dr Koplewicz and Dax discuss the problem with calling children normal or abnormal how young people use alcohol and marijuana to self-medicate their social anxiety and how dyslexia can be seen as a gift Dr Koplewicz talks about how peoples attitudes towards science has changed how certain prescriptions can affect a childs development as an adult and the new film Dear Evan HansenView fullsize DaxShepard-08jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851631751851146-H63KGYINWIL1DQPQ5HT5DaxShepard-08jpg View fullsize HaroldKoplewicz-03jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851631751868323-Z1EHV8H0B9ALX9MTKI7FHaroldKoplewicz-03jpg View fullsize DaxShepardMonicaPadman-03jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851631751859345-W3VNFA4LKFHTT1F462QZDaxShepard26MonicaPadman-03jpg View fullsize HaroldKoplewicz-06jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851631751888139-1OE0YS88MW0CACO7UFKQHaroldKoplewicz-06jpg View fullsize MonicaPadman-09jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851631751918781-4FNAMGWINRLTDXDDJQD2MonicaPadman-09jpg View fullsize HaroldKoplewicz-12jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851631751899820-1UIIPYVCBVPH4RP90J7WHaroldKoplewicz-12jpg View fullsize DaxShepard-02jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851631751958618-3N2O9Z6HIRY5QQCAI4GIDaxShepard-02jpg View fullsize HaroldKoplewicz-10jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851631751945501-IU6FZUT4IC98XPNGSAOSHaroldKoplewicz-10jpg View fullsize AEHaroldKoplewicz-02jpghttpsimagessquarespace-cdncomcontentv159f76c9af14aa1219138e4851631751836938-DTX4R73MAYFU70HJH7DPAEHaroldKoplewicz-02jpgDr Harold S Koplewicz childmindinstitutehttpswwwinstagramcomchildmindinstituteArmchair Expert armchairexppodhttpswwwinstagramcomarmchairexppodDax Shepard daxshepardhttpswwwinstagramcomdaxshepardCreated Produced by Dax Shepardhttpsinstagramcomdaxshepard Monica Padmanhttpswwwinstagramcommlpadman Rob HolyszhttpswwwinstagramcomwobbywobHosted by Dax ShepardEdited by Monica Padman Laura MosesMixed Mastered by Daniel Good
Thu, 16 Sep 2021
Life Science Stories You Won't Want to Miss
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